Matplotlib Subplots and Grid Layouts

Create a multi-panel figure with complex layout:

Figure Overview:
- Total panels: [count]
- Layout complexity: [regular grid/mixed sizes/custom]
- Shared elements: [axes/legends/titles]
- Figure size: [width x height inches]

Layout Specification:

Option 1: Regular Grid
- Rows: [count]
- Columns: [count]
- Equal sizing: [yes/no]

Option 2: Mixed Panel Sizes
- Large panels: [position and span]
- Small panels: [positions]
- Custom arrangement: [describe]

Option 3: Inset Panels
- Main figure: [what]
- Inset position: [where]
- Inset content: [zoom/detail/related]

Panel Contents:
Panel 1:
- Chart type: [specify]
- Data: [describe]
- Special features: [twinx, colorbar, etc.]

Panel 2:
- Chart type: [specify]
- Data: [describe]
- Special features: [if any]

[Continue for all panels]

Shared Elements:
- Shared X-axis: [which panels]
- Shared Y-axis: [which panels]
- Common legend: [content and position]
- Figure title: [suptitle text]
- Panel labels: [(a), (b), (c) style]

Spacing and Layout:
- Padding: [wspace, hspace]
- Margins: [left, right, top, bottom]
- Constrained layout: [yes/no]
- Tight layout: [yes/no]

Provide complete code using appropriate method:
- plt.subplots() for regular grids
- GridSpec for complex layouts
- subplot2grid for specific placements
- add_axes for insets